With Arsenal and C*ty both running United close the pressure is on United to maintain their lead at the top of the table.
Sir Alex has thus answered the call with a strong side to deal with the challenge that Wolves represent.
Rafael returns at right back whilst Fletcher steps back into the starting line up despite a facial injury on Tuesday.
Sir Alex has also chosen to continue with Rooney and Berbatov up top in a 4-4-2.
Starting XI: Van der Sar; Rafael, Vidic, Ferdinand, Evra; Nani, Carrick, Fletcher, Giggs; Rooney, Berbatov
Subs: Kuszczak, Owen, Anderson, Hernandez, Scholes, O’Shea, J. Evans
Edit: Ferdinand picked up an injury in the warm out so Jonny Evans steps in for him
With Rooney back on the goal trail and Berbatov on fire Bet 365 are offering odds of 5/2 for both to reach the targets Sir Alex has set for them 10 for Rooney and 30 for Berbatov so why not put a few quid on it? Click the banner below