With the second leg of the Champions League quarter final looming large , Sir Alex has opted to make changes to the team that triumphed at Stamford Bridge on Wednesday.
Injury forced Rafael to sit this one out whilst Wayne Rooney misses out due to suspension so Berbatov starts up top whilst John O’Shea comes in at right back.
There is a place for Anderson in the starting line up after his brace against Man City’s reserves during the week whilst Hernandez drops to the bench.
Starting XI: Kuszczak; O’Shea, Smalling, Vidic, Evra; Valencia, Scholes, Anderson, Gibson, Nani; Berbatov
Subs: Van Der Sar, Brown, Owen, Park, Carrick, Fabio and Hernandez