No Valencia means Sir Alex names a different team to the one that beat Liverpool whilst long term absentees Young, Vidic, Smalling and Jones further impact on Sir Alex’s options.
Starting XI: Lindegaard, Rafael, Evra, Ferdinand, Evans, Scholes, Nani, Giggs, Carrick, Kagawa, van Persie
Subs: De Gea, Anderson, Rooney, Hernandez, Welbeck, Cleverley, Wootton