United will hope to take 3 points but will be weary of The Saints who should they have a bit of bite about them when they took on Man City at The Etihad.
The return of Rio Ferdinand should alleviate some of the pressure on United’s back line, having had to draft Michael Carrick in as an emergency center back. His return means Carrick can return to midfield where he partners Cleverley.
Starting XI: Lindegaard; Rafael, Ferdinand, Vidic, Evra; Carrick, Cleverley; Valencia, Kagawa, Welbeck; RVP
Subs: De Gea, Evans, Giggs, Hernandez, Nani, Scholes, Powell